Radiation Damage to DNA: The Indirect Effect of Low-Energy Electrons
نویسندگان
چکیده
منابع مشابه
Effect of Exposure to Ionizing Radiation on Biomarker of Oxidative Damage of DNA
Introduction: one of the most important complications of exposure to ionizing radiation is emergence of cancer tumors, which happens as a result of oxidative DNA. Therefore, the present study was conducted, aimed to measuring 8-DIHYDROxy- 2’- DEOXYGUANOSINE (8-OHdG) level in radiographers’ urine as oxidative damage biomarker, as well as comparing this biomarker with cumulative effective doses....
متن کاملMechanism and site of attack for direct damage to DNA by low-energy electrons.
We report results on the desorption of OH- induced by 0-19 eV electrons incident on self-assembled monolayer films made of single and double DNA strands of different orientations with respect to a gold substrate. Such measurements make it possible to deduce the mechanism and site of OH- formation within a biomolecule as complex as DNA. This type of damage is attributed to dissociative electron ...
متن کاملDoes Hze Radiation-induced Dna Damage Differ from Low-energy High Let Radiation Damage?
METHODS We have used 1 GeV/u and 600 MeV/u iron ions at NSRL, 300 kVp X-rays and 25 MeV/u nitrogen ions from the 88” cyclotron at Lawrence Berkeley National Laboratory. For measurements of DNA double-strand breaks we are using pulsed-field gel electrophoresis (PFGE) with a dual label technique that includes control samples in each lane and the use of the most sensitive part of the FAR vs dose c...
متن کاملthe role of russia in transmission of energy from central asia and caucuses to european union
پس ازفروپاشی شوروی،رشد منابع نفت و گاز، آسیای میانه و قفقاز را در یک بازی ژئوپلتیکی انرژی قرار داده است. با در نظر گرفتن این منابع هیدروکربنی، این منطقه به یک میدانجنگ و رقابت تجاری برای بازی های ژئوپلتیکی قدرت های بزرگ جهانی تبدیل شده است. روسیه منطقه را به عنوان حیات خلوت خود تلقی نموده و علاقمند به حفظ حضورش می باشد تا همانند گذشته گاز طبیعی را به وسیله خط لوله مرکزی دریافت و به عنوان یک واس...
15 صفحه اولDamage to model DNA fragments from very low-energy (<1 eV) electrons.
Although electrons having enough energy to ionize or electronically excite DNA have long been known to cause strand breaks (i.e., bond cleavages), only recently has it been suggested that even lower-energy electrons (most recently 1 eV and below) can also damage DNA. The findings of the present work suggest that, while DNA bases can attach electrons having kinetic energies in the 1 eV range and...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: The Journal of Physical Chemistry Letters
سال: 2013
ISSN: 1948-7185
DOI: 10.1021/jz4000998